Sheffield on UK Map


The University of Sheffield Gene Therapy Innovation and Manufacturing Centre (GTIMC)

Exterior of GTIMC building Sheffield’s GTIMC, led by Professor Mimoun Azzouz, builds on a strong history of translational gene therapy research at the University of Sheffield and partners. The centre includes a state-of-the-art GMP manufacturing facility, located in the University of Sheffield’s Innovation District, that will support gene therapy projects emerging from UK universities. The facility will provide clinical grade AAV material for human trials at NHS sites within the national network. The GTIMC will deliver translational and regulatory support alongside an extensive training and skills programme to enable upskilling and address shortage of skills in GMP manufacturing and process development.

View of research working in a cleanroom in the GTIMC

Professor Mimoun Azzouz
Professor Mimoun Azzouz



  • Director: Professor Mimoun Azzouz
  • Head of Process Development: Professor Mark Dickman
  • Head of Skills and Training: Professor Janine Kirby
  • Head of Production: Dr Toby Gamlen
  • Business Development Manager: Dr Isabel Christie
  • Head of Projects: Dr Joe Cartwright
  • Production Lead: Dr Eva Karyka
  • Process and Development Lead: Dr Joseph Scarrott
  • Head of Quality: Michael Reid
  • QA Specialist: Hannah Russell
  • Quality Control Lead: Andy Tomlin
  • Quality Control Technician: Meghan Sullivan
  • Quality Control Technician: Panos Vasilopoulos
  • GMP Technician Lead: Esha Bagi
  • Manufacturing Technician: Shafika Adlard
  • Manufacturing Technician: Poorvaja Jagadeesan
  • GTIMC Administrative Officer: Laura Haslam

Sheffield GTIMC Hub Timeline

August 21
August 2022
October 2022
December 2022
January 2023
February 2023
March 2023
July 2026

Project Launch

New building completion

Tech transfer of AAV platform complete

Scale-up to 50L complete

First validation studies commence

Official opening event

First GMP vector manufactured

Transition to self-sustaining Hub

Hub Locations